Joliet Jewish Congregation
Joliet, IL:
Study Adds Evidence That Flaws in a Tumor's Genetic Mending Kit Drive Treatment Response to Immunotherapy Drugs
In an expanded, three-year clinical trial of 86 patients with colorectal and 11 other kinds of cancer that have so-called ‘mismatch repair’ genetic defects, scientists at Johns Hopkins Medicine and its Bloomberg~Kimmel Institute for Cancer Immunotherapy have found that half of the patients respond to an immunotherapy drug called pembrolizumab (Keytruda). In a report on the findings, which led the U.S. Food and Drug Administration to approve expanded use of pembrolizumab for patients, the researchers also say they found evidence that the immune responses closely aligned with mutations found in their cancers. The report is published online in the June…
How to Live Longer: Researchers Find New Genetic Clues
In a new analysis, researchers explore whether people live longer because they avoid disease or because they possess some anti-aging secret
How Do Life-Changing Drugs Get to Patients?
Clinical trials are generally considered to be biopharmaceutical, medical or health-related research studies that use volunteer participants to test new medi...
Genetic Insights About Health Risks Limited By Lack Of Diversity, Study Finds
A study in the New England Journal of Medicine detailed how the diagnoses of risk for a common hereditary heart disease may have been skewed because studies have traditionally had low numbers of bl…
How studying the rarest of diseases could save millions of lives
A rare disease is one that affects fewer than five in 10,000 people. You might wonder why anyone would dedicate their life to studying a disease when only a handful of people would benefit from a cure. Why not study one of the big killers, such as cancer, tuberculosis or malaria?
Questions to Ask about Treatment Clinical Trials
Suggested questions to ask your doctor, if you are thinking about taking part in a clinical trial.
Drug combo reversed plaque buildup in heart patients’ arteries
New cholesterol-busting PCSK9 inhibitors may one day supplement or even replace the statins that millions of Americans take to reduce their risk of heart attack and stroke.
Big Data Peeps At Your Medical Records To Find Drug Problems
It's been tough to identify the problems that only turn up after medicines are on the market. An experimental project is now combing through data to get earlier, more accurate warnings.
Genetic testing brings the question: Should I know?
The predictive genetic testing industry has blossomed in recent years, both in terms of the of conditions that can be tested for and the ease with which the tests can
What is genetic testing?
Genetic testing, especially in relation to breast cancer risk, has become a common topic in the medical world as technology for detection has advanced. Genetic testing looks for gene changes that a…
The ABCs of DNA: Should You Consider Genetic Testing?
As humans, we each have 46 chromosomes, containing about 20,000 genes. These sequences of letters serve as the body’s instructions. Genetic tests allow us to look at each sequence to see if there are variants, known as mutations. When present, mutations increase an individual’s risk for developing a disease, such as cancer. There are actually three different types of genetic
What Secrets Can Genetic Tests Really Reveal?
What does the information provided in direct-to-consumer genetic tests really reveal about your health, ethnic makeup and ancestry?
WATCH: What you should know about cardiac genetic testing
If you had the opportunity to look into the future and see what health risks might affect you, would you take it?
What Does It Mean to Spell Check Your Genetic Code?
Delaney Van Riper has a rare genetic disorder called CMT that impacts the nerve signals going to her arms and legs. She has muscle atrophy and tightened ligaments, which makes her prone to tripping and falling. Doctors are using the gene-editing technology known as CRISPR to snip out the mutation in her DNA.
Genetic testing: It only works if you know how to use it
For City of Hope scientists, identifying mutations to predict cancer risk isn’t enough. They're also teaching others to use these genetic testing tools.
Woman shares story of how genetic testing helped find her the right medicine
One woman shares her story of how she suffered through terrible side effects from anti-depressants until she found the right type of medicine thanks to genetic testing.
How Real World Evidence is Changing Pharma
NOVEMBER 2, 2017<br>Historically, regulatory approval was the primary focus of drug development, and everything drove toward achieving that milestone. In today’s world, the focus has extended well beyond product approval and launch. Payers, regulatory authorities, physicians, patients and sponsors want to know how a product performs in the real world. They’re looking for a clear picture of real drug performance in a diverse population of…
Why physician burnout treatment doesn’t work
You cannot create an effective program if you do not know what is going on with your staff.
But Physicians And Drug Developers Want To Know
AI relates often imperceptible observations to outcome in a fashion that’s unapologetically oblivious to mechanism, which challenges physicians and drug developers by explicitly severing utility from foundational scientific understanding.
